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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f8280029f5df2ce36e07bfe488c1fddab7e9407c565038c078fd57fb37c36c02' 
  AND token = 'VI3Rkk/kbredH6xuV9QaEWQy4kb7AjQVtt2zsKNQs8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}