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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f5991536729aadc04fdb49f6002f3b450b2ae45110c7099f359a31e1872cc9e9' 
  AND token = 'cna7lYLKxaMgtytP00gXE8+o1t5eBOyJpfE607J7EFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}