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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd8e64aa2e573eee26577f07ce49b51430796a166b936c75fd89b57900853fb33' 
  AND token = 'kiF2aULXsvu1OI8FFasur9rnBmO97+jdw69YSnAorjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}