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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a5092d843df9270e7d09058bef82808860f71e8786de66009996f5c6583e54b' 
  AND token = 'IjnXY/q3djo2jmgKA6hVsMLlgDj0+McA3YcZDEdC5jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}