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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a14201d56d6ce575bf535c9658a3ef0a239a0551b2ddca3d10778402542c84bc' 
  AND token = 'I8IPQZ1NlTcP3/dPwwRbigZ1P4ISYO67vFOTv1wWmVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}