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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '215e24b01f5d9b2c20de90e78075878f431880eb2016a305050b7ce7044f9b6b' 
  AND token = '27un/+Ya707fSFK7zJAz8pkfTzgA6YonO9mXlVmm9MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}