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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0217620d663ef91bde858873a38c402c4de780a162c0c9e21a4a9a3dbcd20886' 
  AND token = 'WUEoz1nhMCXsRpq4UYwMe0j3SjRgdznQv773tWgQ0KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}