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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3df1f4e95215e1e578e5d6b118be7804c99e10b80a815ee0edc93f0ceb383879' 
  AND token = 'f9TIK6zeR0NpyBi2xRRk1I/umHCiOXCMvIBU9/Xo2ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}