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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '14756f7bc4c7bd68a4e55890b5f2c7ce64f0082078dce25c5ec8a818140c8a5f' 
  AND token = '65oWYr2TKS8INdjPcOMXjMn1wxy077RPIuKyJtE/ik4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}