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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'efe7df30e5c8304c331f140b0c4bf8c97e48d94fde08079647a5bca8270a3a0b' 
  AND token = 'gsL2FEoq6He38jlHUFBsCb8NS6S8vJ8GjzMAZlqSM2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}