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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '066e308b5d7dcf7507efb60b1d3c6ef94b1bed9ec443d08d9ab67c8e79bba470' 
  AND token = 'DB83zCFTUoznX6+mVrjMiEVCknIS1bStoKI9pxEWnu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}