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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd547db78ff5d79cef271aa66ce896d0777357618f28f5d8866ba354a35f55270' 
  AND token = 'Z+8Z+aQ9L428CdPtkRStupaEwEZIh2fCnTwZKIRzmQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}