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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c2444530a24d680a331595c2912c9aa5310c0f27417cf07d6ae961fa1d1ad645' 
  AND token = '6jIvoEqdVvYq0D6/9Iz2NrwyhUAzFIBiaPcOUH6ez+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}