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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '423f781f46ba6b3a608da48417000024e4177532e483105d356dec14b9a1a6b3' 
  AND token = 'hZGYJ1LwvoECf1rQhSaf2GMtM7YXGdpt3MFtAa/dxOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}