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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8cdab71459bd032c54a71589e1516a3a96aef9aef0fc2e6d9da003cbfe1df905' 
  AND token = '+31PK0X87+6j1542WlxhGhsfrEWasVCPmyhclT3g0Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}