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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e21d206f1fcffecc8402f1d074e653b49afd612cb788121753a508bd0f6acd8' 
  AND token = 'GbsfE/N7z1dGHsPv6544yDZZb+MCzTD9USckM9fRmwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}