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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6c2a4d6225c8158a41d2be90b638de152220ad275a49f0e0c6d890041da54272' 
  AND token = 'fkdu0jOEPyksj1nih+D96hjcJJU1gi3/EHYfcFxU9Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}