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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5aa9e3b180382680496f306268429d106b555635632ede0a88ccb598c3f4f7dc' 
  AND token = 'OoGer5OxzhgAvkGyOj78updDCsRXNB0jzU42X0UlsDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}