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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50c272afd2a753681bda4c295d0f0f46b72178b13d6c21a15d2076cb73504658' 
  AND token = 'dir1LhDptzfLNgxpMGj72PCGb5AtWKd4haMoN/Lrd9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}