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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0fd5ae7a41d158eb14bd4ab052a3fcce4893dce33b75dffbda01f728dc8460ac' 
  AND token = 'FkQwFh3Tzpki4iq4FXI+/06IqtyBZBctCIOrjmdXE54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}