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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c0c178a12e10d1f8ede917a51bf3f9a8a4625c00214a03ecee5fd79385ec0a1' 
  AND token = 'gqNjs3yyas4zjg7/6RE3Hq+YtZr0jlXJieUz7HggjO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}