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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7677cc534b9b0e1e2b59eab9508cdb3a9e56ffb22337b2320a1a6950820020df' 
  AND token = 'Z/np5ozcdZ0/obDkrRHo149qfaZqD/4lHMdkRCK3RGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}