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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c59925d10f56b1379b6b910e5a37633a040d2079137971381d4d469732b5f804' 
  AND token = '2EANYpWJEnDN69JJckyVP1F8bFNHMclcn+q7aSqoFAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}