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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f504d2e2e87e85d5392e0ae3728fa1191d71b13bd5cb1fcf105cc05eaf7c407' 
  AND token = 'AwA2ORWRwFWrHDFszHRwLUWXHu7aZI4wf/BRCAJ8llc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}