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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1f6021e76720d7622737fa691d1bf160bc56966d797ecebc463a010e2aea0a91' 
  AND token = 'L2mAnkWNhuZ3iyA9S7hpMNSP462xhJDHk7LpRclsFvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}