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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ee7a3aedd5017e8e412c6aecd3ac438dfda265901ecd55cee05508496885b27' 
  AND token = 'py6+avKNWTnOSc3vvPUDbDiTeo47d8yDfXGitvv+tmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}