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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fb4dbd22007410512f81bf5238ee919d1514497378c66286ab8c5743b70a11c5' 
  AND token = 'VG+7eEapSnzhZssGuMEluj6phxxUbuoL+kE1cY4s5o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}