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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c2b1951e17df6406410abec274d4daa1b5b6bd66decbbcee4f9826905cdc281f' 
  AND token = '991+0LUoaAobytNNrYwxEO3Hio2P8yiZsc9LmDWm2lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}