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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10435b29ede2743984e9fd381b247393079601acb6cde1417636010775cc4e6f' 
  AND token = 'mq3HbiybTuXLic2JTGXOCnWVTOswXeQ0RIlv24AaZrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}