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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '729a4dbc5fd6557522ccd27dd8cd82bb4d654b5a6a71162bcc1c9328187f0839' 
  AND token = 'jBAQI8Y10RgJRsRd9qJZ3cUj4pNSbscAXgVw5cahDN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}