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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '40f4e77ffbb44f86aaf78d60e52edeff250b924c70d99d8244f1e627f2c69327' 
  AND token = '/Xu2PF6fyM8E6Vg2di48gqB5yLh0aqiAmhLkJRjWtwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}