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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '621ab82f2214ba60dc217ab157bc00762063abc4e04402878aa0a77c92af6a2a' 
  AND token = 'ePX3bl2V4PZ4aOdqjPjKV+UJAmZN7vfDfyjdTJm+NJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}