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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '62952d0fe8e524b4d460c8080daf453a7d53654f8db34e88b1e4cece938aa403' 
  AND token = 'VAgVq7N7uxS/BQtPWWYyUj1+5pi63GpkoRo3p/dG7lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}