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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e42ae0d89a0b6bec6b7e79c6ee14163055cfd15312f7849361592793d546f4f' 
  AND token = 'uhAa1WeEOCanO3ZgA8HVf9ZhKnudzd7c5VlKbeSXiNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}