SELECT 
  1 
FROM 
  cscart_aprilec_print_temp_designs 
WHERE 
  session_id = 'KE7L-9ZKH-GKK6-Y0AM-U1H9-383H-Y7GP-NUDF' 
  AND product_id = 72 
  AND expires_at > 1777905652 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}