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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f0b40106661e6e9c61e44c6546f4e2655c17399246bbd9638023b333da0ad721' 
  AND token = '21R1sSttXmnV7xqE9gwKBzEf0XwV6PoIrPaOnCiI41w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}