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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '67f6ae1b96f298b13554e53739e65b0b362436f9692f71a606bf58656af4c894' 
  AND token = 'H4qfX3IAzdAs5cAP0adW4OXY5FNYOzz1MOk9XBSM8XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}