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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22f67a66099cf68c177e57f61d18811c71a385fc90c88aa12a02bf122713f8e4' 
  AND token = 'sgXEOsl+lxtbqHI69E4ei/pkQ3FH1O2DMyCEUfOuL34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}