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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65bd6853b3854a240d0d9a0d0478e43d9435c251c211fd6367e08f947d960018' 
  AND token = 'MYFBza7MwYKXFUXWobr0ASxSZGdXCRdHw4Ui3KGBD50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}