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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a307dd79eeb4c383a19a1e40dc7901e724cd30f21a72cead954aec75b69865e2' 
  AND token = 'bOH9SW8MZI0ayZMopJ6zS/d3/4ejJOkODSjwNV8JtiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}