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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '60cd1b25caa40fb6303aac467bdd8f564c1729c075d180f3509bf6ab866e41a7' 
  AND token = 'frokzQ23k0OCdpUO/0l64/gjgGaHGY279MlXJeV7MPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}