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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd5452a2d8e00fc6b483ce0059e056edcc6c713593f4eddaef75545e34bde82ce' 
  AND token = 'q05YfjFtuOIg+YBS4owZNyP7JnDZhMN7CRA1d6+eQVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}