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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1587c063866f15a5b45ab917f41b17155d7b167790376ff2c1c937c9fec7062b' 
  AND token = 'UF5Lv7nfn7AKK7aski1NMy+jOdSNgzYKjPwLgVtfeBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}