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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80d1498a6be8550a45c9873862c59017f24e0a57785e865f45c43cb9e029d446' 
  AND token = 'gn85ep5La1ne3fR8ZS0QPDzmgyq6SJIrz9trqM/WwiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}