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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1cc3e1b586aca175a53c80207c22f9af153287cccd0fbcc2a4a745669319a67a' 
  AND token = '1YLRUovLu/COppmoMKXbyx4Jt9Sp/WgLo0hKHN1zSDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}