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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64df3f5ee33b4d9d722576189399a3f5a69a93cd8f3e5d426413f01dc28a2dc5' 
  AND token = 'sMfjG59ze308LmmQMfvV9fB3YTufaTsvYb4vLMC5M2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}