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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8284c542c004f1af6b07d6e3e1666ebc0f320b399e1e1df560b4923a84685b5f' 
  AND token = 'NXq1vsNAczHStyDCmMZp3x07EEn/9fvGE8/HicfG77A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}