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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41ab493acb67e73a60ca88e0e7a416c050cbb694a291a9cb8fcb6ca1355dbc1c' 
  AND token = 'A+Ypcp3WODsb8XBUX0wIwn9xwO1MiXHRJEgQa/mODt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}