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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c5c83e1fb110c91053d51e3f84c607aba29f30c0c9a8a158fc1b4a545e345d4' 
  AND token = 'E+Pq7bRmNvm+c6JHbSylgH+SeLmA62B/6bgpaWPPM4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}