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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'af0fda1fe25fcfdc9515955139703ac48ea2eafda283c867824bd26672430156' 
  AND token = '5vG4TwviEO4H3045/1fiytDu2DkTaWfj9YCDAzq/XlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}